Santa Fe Institute

Events News

Science On Screen continues May 8 with Simon DeDeo and 'Sneakers'
April 30, 2013 -

The popular Science On Screen series returns to Santa Fe Wednesday evening, May 8, with Simon DeDeo and the 1992 cult hacker film Sneakers.

Video: How social media might help you survive the next big disaster
March 25, 2013 -

SFI's 2013 Community Lecture series debuted March 14 with UC-Boulder's Leysia Palen describing how victims, observers, and “citizen-responders” are using modern technology to participate in disaster response. Watch ...

Climate scientists James Hansen, at SFI, calls for energy sources to foot their 'true' costs
Feb. 22, 2013 -

Speaking at SFI yesterday, noted climate scientist James Hansen told an overflow crowd that efforts to stem climate change will be ineffectual as long as fossil fuels remain the cheapest ...

SFI's successful crowdfunding campaign will help scientists study indigenous people
Dec. 14, 2012 -

SFI's crowdfunding campaign has reached its goal. The resulting research will help scientists preserve the threatened landscapes on which indigenous human groups depend. 

The Gods Must Be Crazy with Murray Gell-Mann
Dec. 13, 2012 -

The 2012 Science On Screen series in Santa Fe wrapped up December 13 to a full house, with "The Gods Must Be Crazy" and Murray Gell-Mann's distinctive insight and ...

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Cancer as a Failure of Multicellularity: The Role of Cellular Evolution

Seminar

August 07, 2013
12:15 PM
Collins Conference Room

John Pepper (National Cancer Institute)

Abstract.   Cancer results from a process of cellular evolution. Key cancer vulnerabilities and defenses arose from the ancient evolutionary transition from single-celled to multicellular organisms. Because cellular evolution leads inexorably to cancer, organismal evolution has organized cell reproduction into patterns that are less subject to cellular evolution. We used an agent-based computational model of evolution inside tissues to evaluate the hypothesis that cell differentiation is crucial to suppressing cellular evolution within the body. The hypothesis was supported. If this most basic safeguard is compromised, all the obstacles to cancer built by organismal evolution are quickly dismantled by cellular evolution within the organism. Other simulations addressed the origins of tissue invasion and metastasis.

Purpose: Research Collaboration

SFI Host: Jennifer Dunne

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  • * SFI community lectures are free, open, & accessible to the public.
  • * Seminars & colloquia are geared for scientists but free & open to the interested public.
  • * All other SFI events are by invitation only.
  • * Note: We are unable to accommodate members of the public for SFI's limited lunch service; you're welcome to bring your own.